Endocrine Abstracts

Introduction: Asprosin, a novel adipokine, is a circulating hormone mainly secreted by white adipose tissue. Asprosin is encoded by the penultimate 2 exons of the fibrillin 1 (FBN1) gene. Protein product of FBN1 is profibrillin-1, which undergoes a proteolytic cleavage by furin enzyme to produce mature fibrillin-1 and asprosin. Literature data indicated that asprosin is involved in the development of diabetes, obesity, cardiomyopathy, cancer, and polycystic o...

Introduction: Omentin, also known as intelectin-1 (ITLN1), is a novel adipokine produced predominantly by visceral adipose tissue, which improves insulin sensitivity. Decreased levels of ITLN1 have been reported in the serum of obese and polycystic ovary syndrome patients, as well as in the serum and adipose tissue of obese Meishan (MS) compared to normal weight Large White (LW) pigs. However, the role of ITLN1 in female reproduction at different metabolic status is still unkn...

Background : Omentin, also known as intelectin-1, is a member of the family of adipose tissue-related hormones known as adipokines, that exert anti-inflammatory, anti-atherosclerotic, and cardiovascular protective effects. Omentin expression has been detected in adipocytes as well as in a variety of extra-adipose tissues, including the ovary. Interestingly, omentin expression in the pituitary has been shown to be regulated by pituitary hormones. These observations led us to in...

Visfatin is one of adipokines that particularly regulates metabolic homeostasis. Literature data of the last decade indicate also that visfatin participates in the regulation of ovarian follicles’ steroid synthesis and oocyte maturation in women, mice, hens, and cows. However, there is still a gap in knowledge about the effect of this adipokine on the corpus luteum (CL) functions. Our previous study documented visfatin mRNA and protein expression in the porcine CL. Theref...